Risperidone and clozapine were more cost effective than haloperidol and chlorpromazine in patients with schizophrenia

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Neurocognitive effects of clozapine, olanzapine, risperidone, and haloperidol in patients with chronic schizophrenia or schizoaffective disorder.

OBJECTIVE Newer antipsychotic drugs have shown promise in ameliorating neurocognitive deficits in patients with schizophrenia, but few studies have compared newer antipsychotic drugs with both clozapine and conventional agents, particularly in patients who have had suboptimal response to prior treatments. METHOD The authors examined the effects of clozapine, olanzapine, risperidone, and halop...

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Effectiveness of clozapine, haloperidol and chlorpromazine in schizophrenia during a five-year period.

OBJECTIVE The aim of our study was to evaluate the effects of low doses of clozapine in flexible regime in comparison with haloperidol and chlorpromazine in long term. METHOD The naturalistic study was prospective, active-controlled with 325 adult outpatients of both genders (140 females), with mean year age of 34.8 (range 21-57), suffering from chronic schizophrenia. The first onset of illne...

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Clozapine alone versus clozapine and risperidone for refractory schizophrenia.

BACKGROUND The treatment of schizophrenia with multiple antipsychotic drugs is common, but the benefits and risks are not known. METHODS In a randomized, double-blind study, we evaluated patients with schizophrenia and a poor response to treatment with clozapine. The patients continued to take clozapine and were randomly assigned to receive eight weeks of daily augmentation with 3 mg of rispe...

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Physician extenders were more cost-effective than usual health care In men with hyperchoBestemlemia

and Commentary also published in ACP Journal Club. 1996; 12 5:80. on the marginal costs and effectiveness of each step along the treatment algorithm were not reported. Therefore, the study is more valuable in relation to the mode of treatment delivery than for details about the treatment itself. Pharoah and HoUingvrorth concentrate on variations in effectiveness and cost among different treatme...

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ژورنال

عنوان ژورنال: Evidence-Based Mental Health

سال: 1998

ISSN: 1362-0347

DOI: 10.1136/ebmh.1.2.64